- Conus regius Gmelin, 1791
- Conus regonae Rolán & Trovão, 1990
- Conus regularis G.B.Sowerby I, 1833
- Conus reticulatus Born, 1778
- Conus retifer Menke, 1829
- Conus richardbinghami Petuch, 1993
- Conus richardsae Röckel & Korn, 1992
- Conus richeri Richard & Moolenbeek, 1988
- Conus riosi Petuch, 1986
- Conus rizali Olivera & Biggs, 2010
- Conus robini (Limpalaër & Monnier, 2012)
- Conus rolani Röckel, 1986
- Conus rosalindensis Petuch, 1998
- Conus roseorapum G.Raybaudi & da Motta, 1990
- Conus royaikeni (S.G.Veldsman, 2010)
- Conus rufimaculosus Macpherson, 1959
- Conus sakalava (Monnier & Tenorio, 2017)
- Conus salletae (T.Cossignani, 2014)
- Conus samiae da Motta, 1982
- Conus sandwichensis Walls, 1978
- Conus sanguinolentus Quoy & Gaimard, 1834
- Conus santinii (Monnier & Limpalaër, 2014)
- Conus scabriusculus Dillwyn, 1817
- Conus scalaris Valenciennes, 1832
- Conus scalarissimus da Motta, 1988
- Conus scottjordani (Poppe, Monnier & Tagaro, 2012)
- Conus sculletti Marsh, 1962
- Conus sculpturatus Röckel & da Motta, 1986
- Conus sennottorum Rehder & Abbott, 1951
- Conus sertacinctus Röckel, 1986
- Conus shikamai Coomans, Moolenbeek & Wils, 1985
- Conus simonis Bozzetti, 2010
- Conus sinaiensis (Petuch & Berschauer, 2016)
- Conus sogodensis (Poppe, Monnier & Tagaro, 2012)
- Conus solangeae Bozzetti, 2004
- Conus solomonensis Delsaerdt, 1992
- Conus spectrum Linnaeus, 1758
- Conus splendidulus G.B.Sowerby I, 1833
- Conus sponsalis Hwass, 1792
- Conus spurius Gmelin, 1791
- Conus spurius lorenzianus Dillwyn, 1817
- Conus stercusmuscarum Linnaeus, 1758
- Conus stimpsoni Dall, 1902
- Conus stramineus Lamarck, 1810
- Conus striatellus Link, 1807
- Conus striatus Linnaeus, 1758
- Conus striolatus Kiener, 1848
- Conus stupa (Kuroda, 1956)
- Conus stupella (Kuroda, 1956)
- Conus subulatus Kiener, 1847